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USP11 and RNF2
Data Source:
BioGRID
(pull down)
USP11
RNF2
Description
ubiquitin specific peptidase 11
ring finger protein 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Chromosome
Cytosol
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Molecular Function
RNA Polymerase II Transcription Corepressor Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
RING-like Zinc Finger Domain Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Viral Process
Protein Deubiquitination
Protein Phosphopantetheinylation
Negative Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Germ Cell Development
Anterior/posterior Axis Specification
Gene Expression
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of G0 To G1 Transition
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Ub-specific processing proteases
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Clopidogrel active metabolite levels (
28207573
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Obesity-related traits (
23251661
)
Interacting Genes
21 interacting genes:
BMI1
BRCA2
CBX8
CDKN1A
DECR2
EIF4B
LIMS1
LLGL1
MBD3
MTA2
PCGF2
PML
RANBP9
RELB
RNF2
RPS6KB1
SETDB1
SUMO2
TBL3
TP53
UBC
59 interacting genes:
ABCB1
AMBRA1
AUTS2
BAALC
BMI1
CASP3
CASP9
CBX2
CBX4
DYSF
ERG
H2AC18
H2AC20
H2AC4
H3-4
KAT8
KMT2A
MBD1
MTNR1A
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF6
PGP
PHB2
PHC1
PHC2
PLK1
PSMC4
RING1
RRM1
RYBP
SIK1
SMURF2
SSX2
TARDBP
TFCP2
TSC22D2
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
USP11
USP19
WASHC1
YAF2
Entrez ID
8237
6045
HPRD ID
02081
07028
Ensembl ID
ENSG00000102226
ENSG00000121481
Uniprot IDs
B4DGK3
P51784
Q99496
PDB IDs
4MEL
5OK6
2H0D
3GS2
3H8H
3IXS
3RPG
4R8P
4S3O
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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