TNNT1 and BLOC1S2

Data Source:
BioGRID (two hybrid)

		TNNT1	BLOC1S2
Description		troponin T1, slow skeletal type	biogenesis of lysosomal organelles complex 1 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Striated Muscle Contraction
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Refractive error ( 32231278)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3
Entrez ID		7138	282991
HPRD ID		01841	12526
Ensembl ID		ENSG00000105048	ENSG00000196072
Uniprot IDs		P13805	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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