BLOC1S2 and P4HA3

Data Source:
BioGRID (two hybrid)

		BLOC1S2	P4HA3
Description		biogenesis of lysosomal organelles complex 1 subunit 2	prolyl 4-hydroxylase subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Gamma-tubulin Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding
	Biological Process	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Hippocampal atrophy ( 25625606)
Interacting Genes		35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3	50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A
Entrez ID		282991	283208
HPRD ID		12526	16413
Ensembl ID		ENSG00000196072	ENSG00000149380
Uniprot IDs		A0A087X1N6 F1T0F0 Q6QNY1	Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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