TNNT1 and MORF4L1

Data Source:
BioGRID (two hybrid)

		TNNT1	MORF4L1
Description		troponin T1, slow skeletal type	mortality factor 4 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Double-strand Break Repair Via Homologous Recombination Chromatin Silencing Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways		Striated Muscle Contraction	HATs acetylate histones
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Coronary artery disease ( 32469254 30104761 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	76 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 CALM1 CAMK2B CEP57L1 CWC27 DMAP1 DRAP1 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TULP3 UBP1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449
Entrez ID		7138	10933
HPRD ID		01841	09532
Ensembl ID		ENSG00000105048	ENSG00000185787
Uniprot IDs		P13805	Q9UBU8
PDB IDs			2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE
Enriched GO Terms of Interacting Partners?
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