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TNNT1 and NINL
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TNNT1
NINL
Description
troponin T1, slow skeletal type
ninein like
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Troponin Complex
Centrosome
Cytosol
Microtubule
Microtubule Cytoskeleton
Intercellular Bridge
Molecular Function
Protein Binding
Tropomyosin Binding
Troponin T Binding
Calcium Ion Binding
Protein Binding
Biological Process
Skeletal Muscle Contraction
Muscle Contraction
Transition Between Fast And Slow Fiber
Muscle Filament Sliding
Slow-twitch Skeletal Muscle Fiber Contraction
Sarcomere Organization
Negative Regulation Of Muscle Contraction
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring At Centrosome
Ciliary Basal Body-plasma Membrane Docking
Pathways
Striated Muscle Contraction
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
Nemaline myopathy
GWAS
Height (
31562340
)
Brain morphology (MOSTest) (
32665545
)
Macular thickness (
30535121
)
Telomere length (
30185882
)
Urate levels (
31578528
)
Interacting Genes
69 interacting genes:
ARMC8
BLOC1S2
BMPR1B
CCDC136
CCDC85B
CHD3
CLIP4
DDX5
EEF1G
FAF1
FXR2
FYN
HAP1
HMGXB4
HSP90AB1
IMMT
KAT5
KRT27
KRT40
LARP1
LDOC1
MARS1
MORF4L1
MYOM2
NACAD
NAGK
NFE2L2
NINL
NSG2
OSBP2
OSM
PI4KA
PLEKHF1
PNMA1
PPFIA1
PRKG1
PSMC5
SBK3
SDCBP2
SEC31A
SERPINA4
SH3GL3
SMAD1
SMAD2
SMURF1
SNW1
TBPL1
TFIP11
TGFBR1
TMEM98
TNNC1
TNNI1
TNNI2
TNNI3
TNNT2
TPM1
TPM3
TRA2A
TRIM63
TSPYL2
TULP3
UBE2D1
VIM
WDCP
ZC3H15
ZKSCAN5
ZMYND19
ZNF250
ZNF768
51 interacting genes:
AKAP17A
APEX2
AURKB
CBY2
CCDC130
CCDC146
CCDC33
CCHCR1
CLEC1B
DCTN5
ELOA
ERBB2
EWSR1
EZH2
FAM107A
FAM161A
GCC1
GPKOW
HAUS1
JUNB
KANSL1
KAT5
KAT7
KRT1
L3MBTL4
LRSAM1
LZTS2
MAD1L1
MBIP
MCM10
PLK1
PRPF18
PRPF3
RBM41
RCOR3
RGS2
RIBC2
RNF40
SH2D4A
SH3BP5L
SYT17
TCEANC
TNNT1
TSPYL4
UTP14A
ZFC3H1
ZFHX3
ZNF250
ZNF417
ZNF426
ZNF646
Entrez ID
7138
22981
HPRD ID
01841
11120
Ensembl ID
ENSG00000105048
ENSG00000101004
Uniprot IDs
P13805
Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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