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TNNT1 and CHD3
Data Source:
BioGRID
(two hybrid)
TNNT1
CHD3
Description
troponin T1, slow skeletal type
chromodomain helicase DNA binding protein 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Troponin Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
NuRD Complex
PML Body
Centriolar Satellite
Molecular Function
Protein Binding
Tropomyosin Binding
Troponin T Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA Helicase Activity
RNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
ATPase Activity
Double-stranded DNA Helicase Activity
Nucleosome-dependent ATPase Activity
Biological Process
Skeletal Muscle Contraction
Muscle Contraction
Transition Between Fast And Slow Fiber
Muscle Filament Sliding
Slow-twitch Skeletal Muscle Fiber Contraction
Sarcomere Organization
Negative Regulation Of Muscle Contraction
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Assembly Or Disassembly
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Spindle Organization
Centrosome Cycle
DNA Duplex Unwinding
ATP-dependent Chromatin Remodeling
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Striated Muscle Contraction
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
SUMOylation of chromatin organization proteins
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
Diseases
Nemaline myopathy
GWAS
Height (
31562340
)
Ischemic stroke (
26089329
)
Macular thickness (
30535121
)
Prostate cancer (
29892016
)
Refractive error (
32231278
)
Stroke (
26089329
)
Interacting Genes
69 interacting genes:
ARMC8
BLOC1S2
BMPR1B
CCDC136
CCDC85B
CHD3
CLIP4
DDX5
EEF1G
FAF1
FXR2
FYN
HAP1
HMGXB4
HSP90AB1
IMMT
KAT5
KRT27
KRT40
LARP1
LDOC1
MARS1
MORF4L1
MYOM2
NACAD
NAGK
NFE2L2
NINL
NSG2
OSBP2
OSM
PI4KA
PLEKHF1
PNMA1
PPFIA1
PRKG1
PSMC5
SBK3
SDCBP2
SEC31A
SERPINA4
SH3GL3
SMAD1
SMAD2
SMURF1
SNW1
TBPL1
TFIP11
TGFBR1
TMEM98
TNNC1
TNNI1
TNNI2
TNNI3
TNNT2
TPM1
TPM3
TRA2A
TRIM63
TSPYL2
TULP3
UBE2D1
VIM
WDCP
ZC3H15
ZKSCAN5
ZMYND19
ZNF250
ZNF768
96 interacting genes:
ACTR1B
ADH5
AIMP2
ATP5IF1
BARD1
BCL6
BHLHE40
C4orf17
CASP6
CASP8
CPE
CRCT1
CREB1
CREBBP
CSTF2
CTBP1
CTTN
ENTR1
FABP4
FBP2
FUBP1
GADD45A
GIT1
GPS2
GSK3B
H3C1
HABP4
HSD17B10
HSPH1
HTT
IK
IKZF1
IKZF3
IMMT
IVNS1ABP
KIF15
KPNA2
KPNB1
LRIF1
LUC7L2
MAFG
MAN2A2
MX1
MYB
NEFL
NR1H2
NR4A1
PAICS
PCMT1
PIAS4
PLK4
PRG2
PRPF40A
PSME1
PTN
PTPRS
PUF60
RAD51
RETREG2
RGS2
RIF1
RPL29
SAFB
SAT1
SATB1
SERBP1
SERF2
SGSM2
SIRT6
SKIL
SLC27A6
SPOP
SRRT
SUMO1
SUMO2
TAL1
TCERG1
THOC7
TNFRSF14
TNNT1
TP53
TP73
TRIM28
TRIM54
TSC22D1
TSPAN6
TTR
TXNDC9
UBA3
UBC
UBE2I
UROD
VIM
XRCC4
YAE1
ZHX1
Entrez ID
7138
1107
HPRD ID
01841
09071
Ensembl ID
ENSG00000105048
ENSG00000170004
Uniprot IDs
P13805
B3KWV4
Q12873
Q2TAZ1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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