BLOC1S2 and ARFIP2

Data Source:
BioGRID (two hybrid)

		BLOC1S2	ARFIP2
Description		biogenesis of lysosomal organelles complex 1 subunit 2	ADP ribosylation factor interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Gamma-tubulin Complex Mitochondrion Lysosomal Membrane BLOC-1 Complex BORC Complex Axon Cytoplasm	Ruffle Cytoplasm Cytosol Plasma Membrane Cell Cortex Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Gamma-tubulin Binding	Protein Binding GTP Binding Phospholipid Binding Protein Domain Specific Binding GTP-dependent Protein Binding Small GTPase Binding Identical Protein Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Membrane Curvature Sensor Activity
	Biological Process	Anterograde Axonal Transport Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization	Intracellular Protein Transport Autophagy Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Malaria ( 31844061)
Interacting Genes		35 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 WASHC1 WASHC3	61 interacting genes: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARFIP1 ARL1 BLOC1S2 C19orf25 CDKN2A CDR1 CEP63 CMTM5 CYTH3 DGAT2L6 DMAP1 DTNBP1 FADS6 FSD2 GOLGA2 GSG1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 KRT16 LNX1 LY6D MAL2 MIEF1 MIEF2 NDRG4 NRDE2 NUP62 PBX3 PKNOX2 PLP2 PPIF RAC1 RAC2 RAC3 REEP5 REL RND1 SCAMP1 SCAMP5 SDCBP SH3GLB1 SMG9 SNX1 SOCS2 STAT3 SYP TMEM255B TRIM54 TTPA USHBP1
Entrez ID		282991	23647
HPRD ID		12526	07209
Ensembl ID		ENSG00000196072	ENSG00000132254
Uniprot IDs		A0A087X1N6 F1T0F0 Q6QNY1	A0A087X1E4 B4DUZ3 B4DXH2 P53365
PDB IDs			1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?
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