TNNT1 and TMEM98

Data Source:
BioGRID (two hybrid)

		TNNT1	TMEM98
Description		troponin T1, slow skeletal type	transmembrane protein 98
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Tropomyosin Binding Troponin T Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction	Negative Regulation Of Protein Processing Negative Regulation Of Myelination T-helper 1 Cell Differentiation Negative Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Protein Localization To Nucleus
Pathways		Striated Muscle Contraction
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Body mass index ( 28552196) Myopia ( 27182965) Platelet distribution width ( 32888494) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		69 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 CLIP4 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT27 KRT40 LARP1 LDOC1 MARS1 MORF4L1 MYOM2 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SBK3 SDCBP2 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TNNT2 TPM1 TPM3 TRA2A TRIM63 TSPYL2 TULP3 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	10 interacting genes: ATP1B3 GJB1 GOLM1 HTR6 MUC1 RABEPK SGTA STOM SUSD3 TNNT1
Entrez ID		7138	26022
HPRD ID		01841	13171
Ensembl ID		ENSG00000105048	ENSG00000006042
Uniprot IDs		P13805	Q9Y2Y6
PDB IDs
Enriched GO Terms of Interacting Partners?
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