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SH2B2 and FAM90A1
Data Source:
BioGRID
(two hybrid)
SH2B2
FAM90A1
Description
SH2B adaptor protein 2
family with sequence similarity 90 member A1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Molecular Function
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Protein Binding
Signaling Adaptor Activity
SH2 Domain Binding
Protein Binding
Biological Process
Blood Coagulation
Insulin Receptor Signaling Pathway
Intracellular Signal Transduction
Antigen Receptor-mediated Signaling Pathway
B Cell Receptor Signaling Pathway
Pathways
Regulation of KIT signaling
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Type 2 diabetes (
31049640
)
Gut microbiota (functional units) (
27694959
)
Interacting Genes
42 interacting genes:
AKT1
ASB6
BTK
CBL
CLK1
CLK3
DUSP13
EGFR
EPOR
ERBB2
ERBB4
FAM124B
FAM90A1
FYN
GRB2
HCK
IL36RN
INSR
JAK1
JAK2
JAK3
KIT
LMO3
LYN
MAGEH1
MCRS1
MET
MTDH
NTRK1
NTRK2
PDLIM7
PLEKHA3
RAB6B
SH2B1
SHC1
SORBS1
SYK
TLE5
TLNRD1
USP2
ZNF414
ZNF417
162 interacting genes:
ABI2
ACTN3
AKAP9
AMOTL2
ANKRD23
ANKRD29
AP2M1
APP
ARHGEF9
ARRDC3
BANP
BCAR1
BEGAIN
BHLHB9
BLZF1
CADPS
CALCOCO2
CARD9
CCDC13
CCDC57
CCN3
CCNC
CCNL2
CDR2
CEP55
CEP70
CEP72
CEP76
CHRDL2
COG6
CYSRT1
DTX3
DVL2
DVL3
EFEMP2
ENKD1
EXOSC8
FAM228A
FHL3
FLACC1
FLOT1
FOSB
FSD2
FXR1
FXR2
FYN
GABPB1
GCSAML
GNPTAB
GOLGA2
GOPC
GPSM1
GRIPAP1
HAND2
HMBOX1
HOMER3
HOMEZ
HOOK2
HSF2BP
ISY1
KANK2
KASH5
KIFC3
KLHL12
KPNA3
KPNA6
KRT31
KRT34
KRT38
KRT40
KRTAP1-1
KRTAP10-8
LDOC1
LHX6
LIMS1
LMO2
LNX1
LRP2BP
LRRK2
LZTS1
LZTS2
MAD1L1
MDFI
MEIS3
MID2
MIPOL1
MLH1
MORN3
MSS51
MTUS2
MYOG
NBPF19
NDUFB7
NOTCH2NLA
NUDT21
OVOL1
PBX1
PBX2
PDLIM7
PFDN5
PICK1
PIH1D1
PLAGL2
POF1B
PPARA
PPP1R13B
PRDM6
PRKAR1B
PRR23B
PSME3
PSTPIP1
RAB11FIP2
RABEP1
RBM48
REL
RHOH
RINT1
ROPN1
RPRD1A
SH2B2
SIAH1
SMAD3
SMARCB1
SNW1
SPRED1
SRPK2
STAC3
STMN2
STX11
TAX1BP1
TEPSIN
TFIP11
TLE5
TMCC2
TRAF2
TRAF4
TRIB3
TRIM23
TRIM27
TRIM42
TRIM54
TRIM55
TRIM69
TRIM9
TRIML2
VRTN
VWC2
ZBTB14
ZBTB16
ZBTB7B
ZBTB8A
ZC2HC1C
ZMYND12
ZNF143
ZNF212
ZNF343
ZNF526
ZNF581
ZNF655
ZNF688
ZNF76
ZWINT
Entrez ID
10603
55138
HPRD ID
16097
07672
Ensembl ID
ENSG00000160999
ENSG00000171847
Uniprot IDs
O14492
Q86YD7
PDB IDs
1Q2H
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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