TRIM55 and CKM

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TRIM55	CKM
Description		tripartite motif containing 55	creatine kinase, M-type
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Extracellular Space Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity
	Biological Process	Signal Transduction	Creatine Metabolic Process Phosphorylation Phosphocreatine Biosynthetic Process
Pathways			Creatine metabolism
Drugs			Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid D-Arginine Phosphocreatine
Diseases
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Creatine kinase in statin users ( 25214527) Intelligence (MTAG) ( 29326435)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	11 interacting genes: CBLC CKB FHL2 HSPB2 MYOC MYOM2 NOS1AP TRIM54 TRIM55 TRIM63 YWHAQ
Entrez ID		84675	1158
HPRD ID		05927	00426
Ensembl ID		ENSG00000147573	ENSG00000104879
Uniprot IDs		Q9BYV6	B2R892 P06732
PDB IDs			1I0E
Enriched GO Terms of Interacting Partners?
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