TRIM55 and STAM

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		TRIM55	STAM
Description		tripartite motif containing 55	signal transducing adaptor molecule
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Cytosol Early Endosome Membrane ESCRT-0 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	SH3/SH2 Adaptor Activity Protein Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Signal Transduction	Intracellular Protein Transport Signal Transduction Positive Regulation Of Signal Transduction Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly
Pathways			EGFR downregulation Metalloprotease DUBs Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	20 interacting genes: ARRB1 HGS JAK1 JAK2 JAK3 MAP3K1 PJA1 PMEPA1 PPP1CA PPP1CC RFFL STAMBP TIMM8A TRIM54 TRIM55 TRIM63 UBC USP15 USP28 USP8
Entrez ID		84675	8027
HPRD ID		05927	03542
Ensembl ID		ENSG00000147573	ENSG00000136738
Uniprot IDs		Q9BYV6	B4DZT2 Q92783
PDB IDs			2L0A 3F1I 3LDZ
Enriched GO Terms of Interacting Partners?
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