TRIM55 and LMCD1

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TRIM55	LMCD1
Description		tripartite motif containing 55	LIM and cysteine rich domains 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Transcription Corepressor Activity Zinc Ion Binding
	Biological Process	Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cardiac Muscle Hypertrophy Cellular Protein Metabolic Process Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways			Surfactant metabolism
Drugs
Diseases
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Brain volume in infants (intracranial brain volume) ( 28763065) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Low high density lipoprotein cholesterol levels ( 26879886) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Rumination (response to stress) ( 30886212) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	7 interacting genes: APP FBXO25 IKBKG NKX3-1 PRKAG3 TRIM55 TRIM63
Entrez ID		84675	29995
HPRD ID		05927	06891
Ensembl ID		ENSG00000147573	ENSG00000071282
Uniprot IDs		Q9BYV6	B4DEY6 B7Z6R5 H7C3D2 Q9NZU5
PDB IDs
Enriched GO Terms of Interacting Partners?
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