TRIM55 and YOD1

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		TRIM55	YOD1
Description		tripartite motif containing 55	YOD1 deubiquitinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Nucleic Acid Binding Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Signal Transduction	Macroautophagy Protein Deubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Systolic blood pressure ( 28234671)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	12 interacting genes: BIRC3 NEDD4 RIPK1 SHARPIN SNCA TRIM54 TRIM55 TRIM63 UBC UBE3A USP15 USP21
Entrez ID		84675	55432
HPRD ID		05927	10312
Ensembl ID		ENSG00000147573	ENSG00000180667
Uniprot IDs		Q9BYV6	Q5VVQ6
PDB IDs			4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
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