CKM and HSPB2

Number of citations of the paper that reports this interaction (PubMedID 26465331)
5

Data Source:
BioGRID (two hybrid)

		CKM	HSPB2
Description		creatine kinase, M-type	heat shock protein family B (small) member 2
Image
GO Annotations	Cellular Component	Extracellular Space Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity	Protein Binding Enzyme Activator Activity
	Biological Process	Creatine Metabolic Process Phosphorylation Phosphocreatine Biosynthetic Process	Response To Unfolded Protein Positive Regulation Of Catalytic Activity
Pathways		Creatine metabolism
Drugs		Creatine (Diaminomethyl-Methyl-Amino)-Acetic Acid D-Arginine Phosphocreatine
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Creatine kinase in statin users ( 25214527) Intelligence (MTAG) ( 29326435)
Interacting Genes		11 interacting genes: CBLC CKB FHL2 HSPB2 MYOC MYOM2 NOS1AP TRIM54 TRIM55 TRIM63 YWHAQ	89 interacting genes: A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BEX4 BGN C1QA CAPZA2 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HSPB3 HSPB8 LGALS1 MAPKAPK5 MB MCCC2 MDH1 MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PGM1 PKP2 PPM1K RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 TATDN1 TCAP THEMIS2 THUMPD2 TNNI3 TTN TXNIP UBL5 WDR1 ZNF335
Entrez ID		1158	3316
HPRD ID		00426	03712
Ensembl ID		ENSG00000104879	ENSG00000170276
Uniprot IDs		B2R892 P06732	A8KAH6 Q16082
PDB IDs		1I0E	6F2R
Enriched GO Terms of Interacting Partners?
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