TRIM55 and DCAF6

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TRIM55	DCAF6
Description		tripartite motif containing 55	DDB1 and CUL4 associated factor 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Signal Transduction	Protein Ubiquitination Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Neddylation
Drugs
Diseases
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Schizophrenia ( 22037555)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	11 interacting genes: ACVR1 AR BMPR1B CUL4A GTF2IRD1 NR3C1 SMAD2 SUPT5H TGFBR1 TRIM55 TRIM63
Entrez ID		84675	55827
HPRD ID		05927	17156
Ensembl ID		ENSG00000147573	ENSG00000143164
Uniprot IDs		Q9BYV6	Q58WW2
PDB IDs			3I7O
Enriched GO Terms of Interacting Partners?
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