TRIM55 and TCAP

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TRIM55	TCAP
Description		tripartite motif containing 55	titin-cap
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Cytosol Z Disc I Band
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Structural Constituent Of Muscle Protein Binding, Bridging Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding
	Biological Process	Signal Transduction	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Limb-girdle muscular dystrophy (LGMD)
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Alcohol consumption ( 31358974) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Ulcerative colitis ( 20228799)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	17 interacting genes: ANKRD2 ATXN1 CRK FAS FYN HSPB2 LHX4 MDM2 MSTN MYOZ1 MYOZ3 PDPK1 RELA SIVA1 TRIM55 TRIM63 TTN
Entrez ID		84675	8557
HPRD ID		05927	05133
Ensembl ID		ENSG00000147573	ENSG00000173991
Uniprot IDs		Q9BYV6	A2TDC0 O15273
PDB IDs			1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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