TRIM55 and TNNI2

Number of citations of the paper that reports this interaction (PubMedID 18157088)
67

Data Source:
BioGRID (two hybrid)

		TRIM55	TNNI2
Description		tripartite motif containing 55	troponin I2, fast skeletal type
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Nucleus Cytosol Troponin Complex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding	Actin Binding Protein Binding Troponin T Binding
	Biological Process	Signal Transduction	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases			Distal arthrogryposis (DA)
GWAS		Coronary heart disease event reduction (statin therapy interaction) ( 22666496) Metabolite levels ( 23823483) Recurrent major depressive disorder ( 29317602)	Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		62 interacting genes: ACTA1 ANKRD1 ATP5F1B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UBE2L3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1	13 interacting genes: ACTB CALM1 ESRRA HNF4G PKD2L1 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2
Entrez ID		84675	7136
HPRD ID		05927	01843
Ensembl ID		ENSG00000147573	ENSG00000130598
Uniprot IDs		Q9BYV6	P48788
PDB IDs			2MKP
Enriched GO Terms of Interacting Partners?
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