PLEKHF2 and DTX2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLEKHF2	DTX2
Description		pleckstrin homology and FYVE domain containing 2	deltex E3 ubiquitin ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding Phosphatidylinositol Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Transport	Notch Signaling Pathway Protein Ubiquitination
Pathways			Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		Radiation response ( 20923822)
Interacting Genes		71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398	44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641
Entrez ID		79666	113878
HPRD ID		15147	16841
Ensembl ID		ENSG00000175895	ENSG00000091073
Uniprot IDs		Q9H8W4	Q86UW9
PDB IDs			6IR0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?