PLEKHF2 and PDP1

		PLEKHF2	PDP1
Description		pleckstrin homology and FYVE domain containing 2	pyruvate dehyrogenase phosphatase catalytic subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Phosphatidylinositol Binding Metal Ion Binding	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Transport	Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Peptidyl-threonine Dephosphorylation Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways			Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases			Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS		Radiation response ( 20923822)
Interacting Genes		71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398	8 interacting genes: ACAT1 CBFA2T2 EGFR FGFR1 PDHA1 PLEKHF2 PRKCD SIRT3
Entrez ID		79666	54704
HPRD ID		15147	16185
Ensembl ID		ENSG00000175895	ENSG00000164951
Uniprot IDs		Q9H8W4	A0A024R9C0 Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?
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