DTX2 and STX12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DTX2	STX12
Description		deltex E3 ubiquitin ligase 2	syntaxin 12
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Membrane	Golgi Membrane Phagophore Assembly Site Synaptic Vesicle Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane BLOC-1 Complex SNARE Complex Early Endosome Membrane Vesicle Membrane Raft Phagocytic Vesicle Recycling Endosome Membrane Postsynaptic Recycling Endosome
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Autophagosome Assembly Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS
Interacting Genes		44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641	12 interacting genes: BLOC1S6 DNAJC5 DTX2 EEA1 EPB42 HOMER1 LMNA NAPA NSG1 SNAP23 SNAP25 SNAP29
Entrez ID		113878	23673
HPRD ID		16841	06059
Ensembl ID		ENSG00000091073	ENSG00000117758
Uniprot IDs		Q86UW9	Q86Y82
PDB IDs		6IR0	2DNX
Enriched GO Terms of Interacting Partners?
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