DTX2 and DTX1

Number of citations of the paper that reports this interaction (PubMedID 11226752)
25

Data Source:
HPRD (two hybrid)

		DTX2	DTX1
Description		deltex E3 ubiquitin ligase 2	deltex E3 ubiquitin ligase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Membrane	Nucleoplasm Cytoplasm Cytosol Nuclear Body
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Notch Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Transcription, DNA-templated Transcription By RNA Polymerase II Cell Surface Receptor Signaling Pathway Notch Signaling Pathway Regulation Of Notch Signaling Pathway Glial Cell Differentiation Protein Ubiquitination Negative Regulation Of T Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Nucleic Acid-templated Transcription Cellular Response To Leukemia Inhibitory Factor
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus	Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS			Body mass index ( 26426971) Coffee consumption ( 29367735) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641	20 interacting genes: DEFA5 DTX2 DTX3 DTX3L EP300 G3BP1 GRB2 ITCH MAP3K1 NOTCH1 NOTCH2 TAX1BP3 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2N UBE2U
Entrez ID		113878	1840
HPRD ID		16841	03991
Ensembl ID		ENSG00000091073	ENSG00000135144
Uniprot IDs		Q86UW9	Q86Y01
PDB IDs		6IR0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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