PLEKHF2 and S100A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PLEKHF2	S100A1
Description		pleckstrin homology and FYVE domain containing 2	S100 calcium binding protein A1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection
	Molecular Function	Protein Binding Phosphatidylinositol Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Protein Transport	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis
Pathways			Regulation of TLR by endogenous ligand
Drugs			Olopatadine
Diseases
GWAS		Radiation response ( 20923822)
Interacting Genes		71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398	27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		79666	6271
HPRD ID		15147	01489
Ensembl ID		ENSG00000175895	ENSG00000160678
Uniprot IDs		Q9H8W4	A0A0S2Z4H2 P23297
PDB IDs			2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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