PLEKHF2 and DUT

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (two hybrid)

		PLEKHF2	DUT
Description		pleckstrin homology and FYVE domain containing 2	deoxyuridine triphosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Nucleus Nucleoplasm Mitochondrion Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol Binding Metal Ion Binding	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding
	Biological Process	Protein Transport	Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Nucleobase-containing Small Molecule Interconversion DUTP Catabolic Process
Pathways
Drugs			Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Radiation response ( 20923822)	Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)
Interacting Genes		71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398	9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID		79666	1854
HPRD ID		15147	03165
Ensembl ID		ENSG00000175895	ENSG00000128951
Uniprot IDs		Q9H8W4	A0A0C4DGL3 H0YNW5 P33316
PDB IDs			1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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