DTX2 and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DTX2	TRIP13
Description		deltex E3 ubiquitin ligase 2	thyroid hormone receptor interactor 13
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Membrane	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Regulation Of Nucleic Acid-templated Transcription
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS			Pancreatic cancer ( 25086665)
Interacting Genes		44 interacting genes: ABHD16A ALKBH4 ARNT2 C1orf94 COQ8A DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS1 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1 ZNF641	83 interacting genes: ADAM15 AMDHD2 ARL11 ARSA ASB13 BUB1B C11orf54 C4orf33 CARD14 CD99 CDC20 CFP COMT CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 INTS11 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 NTAQ1 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA PRKN QARS1 RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR ZNF34 ZNF655
Entrez ID		113878	9319
HPRD ID		16841	05145
Ensembl ID		ENSG00000091073	ENSG00000071539
Uniprot IDs		Q86UW9	Q15645
PDB IDs		6IR0	5VQ9 5VQA 5WC2 6F0X
Enriched GO Terms of Interacting Partners?
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