AIMP2 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AIMP2	PLEKHF2
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Protein Transport
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Reticulocyte fraction of red cells ( 27863252)	Radiation response ( 20923822)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		7965	79666
HPRD ID		02915	15147
Ensembl ID		ENSG00000106305	ENSG00000175895
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	Q9H8W4
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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