AIMP2 and GYS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AIMP2	GYS1
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	glycogen synthase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding Molecular Adaptor Activity	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Glycogen Biosynthetic Process Heart Development
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	10 interacting genes: AIMP2 APP CSNK2A1 GSK3B GYG1 GYG2 IHO1 MAPKAPK5 NHLRC1 PRKACA
Entrez ID		7965	2997
HPRD ID		02915	00721
Ensembl ID		ENSG00000106305	ENSG00000104812
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	P13807
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39
Enriched GO Terms of Interacting Partners?
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