AIMP2 and FUBP1

Number of citations of the paper that reports this interaction (PubMedID 12819782)
50

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		AIMP2	FUBP1
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	far upstream element binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Molecular Adaptor Activity	Single-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Gene Expression
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs			Irofulven
Diseases
GWAS		Reticulocyte fraction of red cells ( 27863252)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Lung cancer in never smokers ( 28604730) Psoriasis ( 28537254)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	15 interacting genes: AIMP2 CCNH CELF1 CHD3 CRMP1 ESR1 GTF2H1 IMMT MYOC PUF60 SIRPA SMN1 SMURF2 TLE1 VIM
Entrez ID		7965	8880
HPRD ID		02915	10349
Ensembl ID		ENSG00000106305	ENSG00000162613
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	A0A384MDX9 B4DT31 Q96AE4
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39	1J4W 2KXH 4LIJ
Enriched GO Terms of Interacting Partners?
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