AIMP2 and DEAF1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		AIMP2	DEAF1
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	DEAF1 transcription factor
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GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nuclear Chromatin Fibrillar Center Extracellular Region Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Molecular Adaptor Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	Negative Regulation Of Transcription By RNA Polymerase II Behavioral Fear Response Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Germ Cell Development Visual Learning Anatomical Structure Morphogenesis Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS		Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	19 interacting genes: AIMP2 ASCC2 CDC37 CDKN1A CDKN2A FHL1 GOLGA3 GSK3A GSK3B HRAS INTS1 LMO4 PELI2 PIN1 PPP1CA PPP1CC RAD23B RIDA TK1
Entrez ID		7965	10522
HPRD ID		02915	04027
Ensembl ID		ENSG00000106305	ENSG00000177030
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	O75398
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39	2JW6 4A24 5UWW
Enriched GO Terms of Interacting Partners?
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