AIMP2 and DARS2

Number of citations of the paper that reports this interaction (PubMedID 9878398)
55

Data Source:
BioGRID (two hybrid)

		AIMP2	DARS2
Description		aminoacyl tRNA synthetase complex interacting multifunctional protein 2	aspartyl-tRNA synthetase 2, mitochondrial
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GO Annotations	Cellular Component	Nucleus Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Molecular Adaptor Activity	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Protein-containing Complex Assembly Positive Regulation Of Neuron Death Positive Regulation Of Aminoacyl-tRNA Ligase Activity	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation	Mitochondrial tRNA aminoacylation
Drugs			L-Aspartic Acid
Diseases			Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL)
GWAS		Reticulocyte fraction of red cells ( 27863252)	Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		48 interacting genes: ACTB AIMP1 APP BCAS2 BEX3 BLOC1S4 BYSL C19orf57 CEP126 CHD3 DARS1 DARS2 DEAF1 DSN1 EPRS1 EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS1 KDR KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PRKN PSME1 SMURF2 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT	4 interacting genes: AIMP2 DPYSL5 EPHA8 KARS1
Entrez ID		7965	55157
HPRD ID		02915	07677
Ensembl ID		ENSG00000106305	ENSG00000117593
Uniprot IDs		A0A024QZY1 A8MU58 Q13155	Q6PI48 Q9H9J7
PDB IDs		4DPG 4YCU 4YCW 5A1N 5A34 5A5H 5Y6L 6ILD 6IY6 6JPV 6K39	4AH6
Enriched GO Terms of Interacting Partners?
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