SEC16A and SEC23A

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		SEC16A	SEC23A
Description		SEC16 homolog A, endoplasmic reticulum export factor	SEC23 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Extrinsic Component Of Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Endoplasmic Reticulum Organization Golgi Organization Substantia Nigra Development Protein Exit From Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Golgi To Plasma Membrane CFTR Protein Transport COPII Vesicle Coating Protein Stabilization Positive Regulation Of Protein Exit From Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Plasma Membrane	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of GTPase Activity COPII Vesicle Coating Protein Localization To Plasma Membrane COPII-coated Vesicle Cargo Loading
Pathways		COPII-mediated vesicle transport	Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases			Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS		Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798 32041948) Eosinophil counts ( 27863252) Height ( 28552196) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 32888494) Squamous cell carcinoma ( 31174203) Triglyceride levels ( 32154731) Ulcerative colitis ( 28067908 21297633)	Metabolite levels ( 23823483) Vitamin D levels ( 29343764)
Interacting Genes		2 interacting genes: MIA3 SEC23A	35 interacting genes: BNIP3 CADPS CDK16 CDK18 CLEC17A DCTN1 DNM2 DTX2 ERGIC3 ERLIN1 FASLG FATE1 GJA8 GLRA2 HOMEZ MFF MIA2 MIA3 MINAR1 NDRG1 PIAS2 RNF19B SDCBP2 SEC16A SEC23B SEC23IP SEC24B SEC24C SEC24D SF1 SLC7A1 SUCLA2 TMEM45B TNFSF14 WBP11
Entrez ID		9919	10484
HPRD ID		11075	06714
Ensembl ID		ENSG00000148396	ENSG00000100934
Uniprot IDs		F1T0I1 O15027	Q15436
PDB IDs			2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX 5KYN 5KYU 5KYW 5KYX 5KYY 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?