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CD74 and TEX11
Data Source:
BioGRID
(two hybrid)
CD74
TEX11
Description
CD74 molecule
testis expressed 11
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Multivesicular Body
Vacuole
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
ER To Golgi Transport Vesicle Membrane
Membrane
Integral Component Of Membrane
Transport Vesicle Membrane
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
Protein-containing Complex
Macrophage Migration Inhibitory Factor Receptor Complex
NOS2-CD74 Complex
MHC Class II Protein Complex
Lysosomal Lumen
Extracellular Exosome
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Synaptonemal Complex
Central Element
Chromosome
Molecular Function
Amyloid-beta Binding
Cytokine Receptor Activity
Protein Binding
Cytokine Binding
MHC Class II Protein Complex Binding
Macrophage Migration Inhibitory Factor Binding
MHC Class II Protein Binding
CD4 Receptor Binding
MHC Class II Protein Binding, Via Antigen Binding Groove
Identical Protein Binding
Protein Folding Chaperone
Nitric-oxide Synthase Binding
Protein Binding
Biological Process
Activation Of MAPK Activity
Prostaglandin Biosynthetic Process
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cytokine-mediated Signaling Pathway
T Cell Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Negative Regulation Of Peptide Secretion
Positive Regulation Of Type 2 Immune Response
Negative Regulation Of Mature B Cell Apoptotic Process
Intracellular Protein Transport
Cell Population Proliferation
Positive Regulation Of Gene Expression
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation
Antigen Processing And Presentation Of Endogenous Antigen
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Negative Regulation Of Cell Migration
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Prostaglandin Biosynthetic Process
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Kinase Activity
Response To Interferon-gamma
Macrophage Migration Inhibitory Factor Signaling Pathway
Regulation Of Macrophage Activation
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of MAPK Cascade
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
T Cell Selection
Positive Thymic T Cell Selection
Negative Thymic T Cell Selection
Negative Regulation Of T Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Monocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Chaperone Cofactor-dependent Protein Refolding
Positive Regulation Of Macrophage Cytokine Production
Protein-containing Complex Assembly
Protein Trimerization
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Neutrophil Chemotaxis
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway
Resolution Of Meiotic Recombination Intermediates
Meiotic Gene Conversion
Male Meiosis Chromosome Segregation
Synaptonemal Complex Assembly
Reciprocal Meiotic Recombination
Male Gonad Development
Fertilization
Negative Regulation Of Apoptotic Process
Chiasma Assembly
Pathways
Cell surface interactions at the vascular wall
MHC class II antigen presentation
Drugs
Diseases
GWAS
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Mean corpuscular volume (
29403010
)
Waist circumference (
28552196
)
Interacting Genes
44 interacting genes:
APP
BET1
C14orf180
CCR1
CD1D
CD44
CLDN19
CLEC7A
CMTM7
CTSF
CTSL
EDDM3B
ERG28
FDFT1
FXYD6
HADHA
HLA-DMA
HLA-DMB
HLA-DPA1
HLA-DPB1
HLA-DQA1
HLA-DQB1
HLA-DRA
LAMTOR5
LPAR3
MAP3K1
MIF
PGA4
PLP1
PLPP4
POMGNT1
PTCH1
RTP2
SEC22A
SERP1
SLC35B1
SMIM1
TEX11
TMEM120B
TMEM243
TMEM254
TMEM60
TMEM97
UPK2
91 interacting genes:
ATXN3
BCL2L2
BEX1
BORCS8
BORCS8-MEF2B
BRMS1L
C10orf82
C2CD6
C6orf226
CBY2
CCDC198
CCND2
CCND3
CD74
CDKN1A
CDKN2D
CENPP
CEP55
CEP85L
CFAP53
CLK1
CNOT7
COL20A1
CXCL14
DMTN
DUSP21
DUSP6
EFHC1
EXOSC1
EXOSC5
FAAP20
FAM156A
FAM161B
FAM217A
FBF1
GATAD2B
GPSM3
GRXCR1
HOXB5
HYI
ING3
KANK2
KCTD10
KIAA0408
KIAA1217
KRT6B
LIN37
LRCH2
LRRC36
LSM2
MAD1L1
MAPK9
MAPKBP1
MORF4L1
MRFAP1
MRFAP1L1
MTA1
MYEF2
NECAB2
NEFL
NRIP1
PIAS1
POM121
PPP1R18
PRPSAP2
PTPDC1
QKI
REXO1L6P
RIBC1
RIBC2
SCAF8
SEPTIN1
SH3GLB2
SHOC1
SNW1
SNX32
SNX6
SNX7
SOX5
STMN2
SUPT5H
TBC1D22B
TCHP
TIPIN
TOPBP1
TSC22D4
TSG101
USP15
UTP14C
VIL1
ZNF414
Entrez ID
972
56159
HPRD ID
00825
02256
Ensembl ID
ENSG00000019582
ENSG00000120498
Uniprot IDs
P04233
Q8IYF3
PDB IDs
1A6A
1ICF
1IIE
1L3H
1MUJ
3PDO
3PGC
3PGD
3QXA
3QXD
4AEN
4AH2
4X5W
5KSU
5KSV
Enriched GO Terms of Interacting Partners
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