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TEX11 and TOPBP1
Data Source:
BioGRID
(two hybrid)
TEX11
TOPBP1
Description
testis expressed 11
DNA topoisomerase II binding protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Synaptonemal Complex
Central Element
Chromosome
Condensed Nuclear Chromosome
Spindle Pole
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Microtubule Organizing Center
Plasma Membrane
Actin Cytoskeleton
Nuclear Body
PML Body
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
DNA Binding
Protein Binding
Protein C-terminus Binding
Identical Protein Binding
Biological Process
Resolution Of Meiotic Recombination Intermediates
Meiotic Gene Conversion
Male Meiosis Chromosome Segregation
Synaptonemal Complex Assembly
Reciprocal Meiotic Recombination
Male Gonad Development
Fertilization
Negative Regulation Of Apoptotic Process
Chiasma Assembly
DNA Metabolic Process
DNA Replication
DNA Replication Initiation
DNA Repair
Cellular Response To DNA Damage Stimulus
Mitotic G2 DNA Damage Checkpoint
Response To Ionizing Radiation
Mitotic DNA Replication Checkpoint
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Mean corpuscular volume (
29403010
)
Waist circumference (
28552196
)
Iron status biomarkers (
19084217
)
Interacting Genes
91 interacting genes:
ATXN3
BCL2L2
BEX1
BORCS8
BORCS8-MEF2B
BRMS1L
C10orf82
C2CD6
C6orf226
CBY2
CCDC198
CCND2
CCND3
CD74
CDKN1A
CDKN2D
CENPP
CEP55
CEP85L
CFAP53
CLK1
CNOT7
COL20A1
CXCL14
DMTN
DUSP21
DUSP6
EFHC1
EXOSC1
EXOSC5
FAAP20
FAM156A
FAM161B
FAM217A
FBF1
GATAD2B
GPSM3
GRXCR1
HOXB5
HYI
ING3
KANK2
KCTD10
KIAA0408
KIAA1217
KRT6B
LIN37
LRCH2
LRRC36
LSM2
MAD1L1
MAPK9
MAPKBP1
MORF4L1
MRFAP1
MRFAP1L1
MTA1
MYEF2
NECAB2
NEFL
NRIP1
PIAS1
POM121
PPP1R18
PRPSAP2
PTPDC1
QKI
REXO1L6P
RIBC1
RIBC2
SCAF8
SEPTIN1
SH3GLB2
SHOC1
SNW1
SNX32
SNX6
SNX7
SOX5
STMN2
SUPT5H
TBC1D22B
TCHP
TIPIN
TOPBP1
TSC22D4
TSG101
USP15
UTP14C
VIL1
ZNF414
32 interacting genes:
ABL1
AKT1
ATM
BLM
BMPR2
BRIP1
CDC45
CHEK1
CLSTN1
E2F1
ESR1
FHL3
GINS1
HUS1
PML
POLE
PPHLN1
PPP1CC
RAD1
RAD9A
RAI1
RBBP8
RHNO1
SF3B2
SMARCAD1
TBC1D4
TCFL5
TEX11
TICRR
TOP2B
UBR5
ZBTB17
Entrez ID
56159
11073
HPRD ID
02256
09678
Ensembl ID
ENSG00000120498
ENSG00000163781
Uniprot IDs
Q8IYF3
A0AV47
A7E2X7
Q05BV8
Q92547
PDB IDs
1WF6
2XNH
2XNK
3AL2
3AL3
3JVE
3OLC
3PD7
3UEN
3UEO
6RML
6RMM
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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