TEX11 and GATAD2B

Data Source:
BioGRID (two hybrid)

		TEX11	GATAD2B
Description		testis expressed 11	GATA zinc finger domain containing 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Chromosome	Chromatin Nucleoplasm NuRD Complex Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Sequence-specific DNA Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Gonad Development Fertilization Negative Regulation Of Apoptotic Process Chiasma Assembly	Negative Regulation Of Transcription By RNA Polymerase II ATP-dependent Chromatin Remodeling
Pathways			HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs
Diseases
GWAS		Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)	Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Height ( 31562340) Lentiform nucleus volume ( 22903471) Number of children ever born ( 27798627) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L C10orf82 C2CD6 C6orf226 CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414	29 interacting genes: CALCOCO2 CDKN2D CEP70 ERCC6 FHL2 GOLGA2 GPSM3 H2AC20 H2BC21 H3C1 H4C1 KAT2B MBD2 MBD3 MTNR1A NGB NME7 NOXA1 PRKAB2 RBPMS RPGRIP1 SBK3 SMAD2 SUMO2 TEX11 TRAF1 TRIM27 USHBP1 ZGPAT
Entrez ID		56159	57459
HPRD ID		02256	15094
Ensembl ID		ENSG00000120498	ENSG00000143614
Uniprot IDs		Q8IYF3	Q8WXI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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