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CD74 and BET1
Data Source:
BioGRID
(two hybrid)
CD74
BET1
Description
CD74 molecule
Bet1 golgi vesicular membrane trafficking protein
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Cytoplasm
Lysosomal Membrane
Multivesicular Body
Vacuole
Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
ER To Golgi Transport Vesicle Membrane
Membrane
Integral Component Of Membrane
Transport Vesicle Membrane
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Trans-Golgi Network Membrane
Protein-containing Complex
Macrophage Migration Inhibitory Factor Receptor Complex
NOS2-CD74 Complex
MHC Class II Protein Complex
Lysosomal Lumen
Extracellular Exosome
Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
Golgi Trans Cisterna
Golgi Membrane
Endoplasmic Reticulum Membrane
Membrane
Transport Vesicle
Integral Component Of Golgi Membrane
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Molecular Function
Amyloid-beta Binding
Cytokine Receptor Activity
Protein Binding
Cytokine Binding
MHC Class II Protein Complex Binding
Macrophage Migration Inhibitory Factor Binding
MHC Class II Protein Binding
CD4 Receptor Binding
MHC Class II Protein Binding, Via Antigen Binding Groove
Identical Protein Binding
Protein Folding Chaperone
Nitric-oxide Synthase Binding
SNAP Receptor Activity
Protein Binding
Biological Process
Activation Of MAPK Activity
Prostaglandin Biosynthetic Process
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cytokine-mediated Signaling Pathway
T Cell Activation Involved In Immune Response
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Negative Regulation Of Peptide Secretion
Positive Regulation Of Type 2 Immune Response
Negative Regulation Of Mature B Cell Apoptotic Process
Intracellular Protein Transport
Cell Population Proliferation
Positive Regulation Of Gene Expression
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation
Antigen Processing And Presentation Of Endogenous Antigen
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Negative Regulation Of Cell Migration
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Prostaglandin Biosynthetic Process
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Kinase Activity
Response To Interferon-gamma
Macrophage Migration Inhibitory Factor Signaling Pathway
Regulation Of Macrophage Activation
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of MAPK Cascade
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
T Cell Selection
Positive Thymic T Cell Selection
Negative Thymic T Cell Selection
Negative Regulation Of T Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Monocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Leukocyte Migration
Chaperone Cofactor-dependent Protein Refolding
Positive Regulation Of Macrophage Cytokine Production
Protein-containing Complex Assembly
Protein Trimerization
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Neutrophil Chemotaxis
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production
Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Transport
COPII Vesicle Coating
Vesicle Fusion With Golgi Apparatus
Pathways
Cell surface interactions at the vascular wall
MHC class II antigen presentation
COPII-mediated vesicle transport
COPI-mediated anterograde transport
Drugs
Diseases
GWAS
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Aging (
22773346
)
Asparaginase hypersensitivity in acute lymphoblastic leukemia (
25987655
)
BRCA1/2-negative high-risk breast cancer (
30323354
)
Obesity-related traits (
23251661
)
World class endurance athleticism (
26824906
)
Interacting Genes
44 interacting genes:
APP
BET1
C14orf180
CCR1
CD1D
CD44
CLDN19
CLEC7A
CMTM7
CTSF
CTSL
EDDM3B
ERG28
FDFT1
FXYD6
HADHA
HLA-DMA
HLA-DMB
HLA-DPA1
HLA-DPB1
HLA-DQA1
HLA-DQB1
HLA-DRA
LAMTOR5
LPAR3
MAP3K1
MIF
PGA4
PLP1
PLPP4
POMGNT1
PTCH1
RTP2
SEC22A
SERP1
SLC35B1
SMIM1
TEX11
TMEM120B
TMEM243
TMEM254
TMEM60
TMEM97
UPK2
52 interacting genes:
ADORA2A
ANKS6
AQP6
ASGR2
ASZ1
BCL2L13
CD74
CD79A
CGRRF1
CISD2
CLDN7
CLEC10A
CRB3
CREB3L1
CYB561
CYBC1
ELOVL4
ERGIC3
FAM174A
FAM209A
FAM210B
FAM9B
GOSR2
GPR152
GPX8
JAGN1
KASH5
KCNJ6
LYPD5
MAGEA6
MFF
MGST3
NAPB
PTGES
REEP4
RETREG3
SLC26A6
SLC7A14
SNTG2
SSMEM1
STX1A
STX1B
STX2
STX4
STX5
TMCO5A
TMEM237
TMEM35A
TMEM52B
TMEM80
TMX2
USHBP1
Entrez ID
972
10282
HPRD ID
00825
16107
Ensembl ID
ENSG00000019582
ENSG00000105829
Uniprot IDs
P04233
O15155
Q53XK0
PDB IDs
1A6A
1ICF
1IIE
1L3H
1MUJ
3PDO
3PGC
3PGD
3QXA
3QXD
4AEN
4AH2
4X5W
5KSU
5KSV
3EGX
Enriched GO Terms of Interacting Partners
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