IPO13 and ALX1

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		IPO13	ALX1
Description		importin 13	ALX homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus Nucleoplasm Golgi Apparatus Nuclear Body
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Import Into Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways
Drugs
Diseases			Frontonasal dysplasia
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300
Entrez ID		9670	8092
HPRD ID		13742	03316
Ensembl ID		ENSG00000117408	ENSG00000180318
Uniprot IDs		O94829	Q15699 V9HWA7
PDB IDs		2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?
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