IPO13 and MAGOH

Data Source:
HPRD (in vitro)

		IPO13	MAGOH
Description		importin 13	mago homolog, exon junction complex subunit
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding
	Biological Process	Protein Import Into Nucleus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	19 interacting genes: ALYREF CEP70 CORO1A DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B RBM8A TADA2A UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		9670	4116
HPRD ID		13742	04005
Ensembl ID		ENSG00000117408	ENSG00000162385
Uniprot IDs		O94829	P61326
PDB IDs		2X19 2XWU 3ZJY	1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P
Enriched GO Terms of Interacting Partners?
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