ALX1 and UROC1

Data Source:
BioGRID (two hybrid)

		ALX1	UROC1
Description		ALX homeobox 1	urocanate hydratase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Golgi Apparatus Nuclear Body	Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Urocanate Hydratase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Histidine Catabolic Process Histidine Catabolic Process To Glutamate And Formamide Histidine Catabolic Process To Glutamate And Formate
Pathways			Histidine catabolism
Drugs
Diseases		Frontonasal dysplasia
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)	Anorectal malformation ( 31136621) Cerebellum cortex volume ( 31530798) Fast beta electroencephalogram ( 28040410) Heel bone mineral density ( 30598549) Periventricular white matter hyperintensities ( 32517579) Post bronchodilator FEV1 ( 26634245) Rapid automised naming of letters ( 30741946) Recurrence of malaria infection (mild or asymptomatic) ( 31667592) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300	1 interacting genes: ALX1
Entrez ID		8092	131669
HPRD ID		03316	08712
Ensembl ID		ENSG00000180318	ENSG00000159650
Uniprot IDs		Q15699 V9HWA7	Q96N76
PDB IDs
Enriched GO Terms of Interacting Partners?
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