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ALX1 and KRTAP4-4
Data Source:
BioGRID
(two hybrid)
ALX1
KRTAP4-4
Description
ALX homeobox 1
keratin associated protein 4-4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Golgi Apparatus
Nuclear Body
Cytosol
Keratin Filament
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Protein Homodimerization Activity
Sequence-specific Double-stranded DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neural Crest Cell Migration
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Skeletal System Morphogenesis
Keratinization
Pathways
Keratinization
Drugs
Diseases
Frontonasal dysplasia
GWAS
Bone mineral density (Ward's triangle area) (
27397699
)
Brain morphology (MOSTest) (
32665545
)
Lung function (FEV1) (
30061609
)
Lung function (FVC) (
30061609
)
Nonsyndromic cleft lip (
31609978
)
Nose size (
27182965
)
Interacting Genes
17 interacting genes:
ALX4
APCS
CLIC3
CREBBP
EEF1D
EP300
GRP
IPO13
KAT5
KRTAP4-4
OR52L1
PACRGL
RARA
RBM45
SRA1
UROC1
ZNF300
67 interacting genes:
ADAMTSL4
ALX1
AQP1
BAG4
CATSPER1
CBX2
CRCT1
CREB5
CYSRT1
GLRX3
GNE
HEY2
HOXA1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-5
KRTAP10-6
KRTAP10-8
KRTAP12-1
KRTAP12-3
KRTAP13-2
KRTAP17-1
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-2
KRTAP4-2
KRTAP4-5
KRTAP5-11
KRTAP5-7
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE3A
LCE3B
LCE3C
LCE3E
LCE4A
LCE5A
MEOX2
NBPF19
NOTCH2NLA
NPDC1
NR4A3
NUFIP2
OTX1
POU4F2
SHFL
SMCP
TNS2
TRIM42
ZNF440
ZNF497
ZNF764
Entrez ID
8092
84616
HPRD ID
03316
13945
Ensembl ID
ENSG00000180318
ENSG00000171396
Uniprot IDs
Q15699
V9HWA7
Q9BYR3
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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