IPO13 and EIF1AX

		IPO13	EIF1AX
Description		importin 13	eukaryotic translation initiation factor 1A X-linked
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Protein Import Into Nucleus	Translational Initiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	9 interacting genes: APP EIF2S1 EIF3C EIF5 EIF5B HSPB1 IKBKG IPO13 RFPL3
Entrez ID		9670	1964
HPRD ID		13742	02174
Ensembl ID		ENSG00000117408	ENSG00000173674
Uniprot IDs		O94829	P47813
PDB IDs		2X19 2XWU 3ZJY	1D7Q 3ZJY 4KZY 4KZZ 6YBW 6ZMW 6ZP4 7A09
Enriched GO Terms of Interacting Partners?
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