IPO13 and PBX4

Data Source:
BioGRID (two hybrid)

		IPO13	PBX4
Description		importin 13	PBX homeobox 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin XY Body Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Protein Import Into Nucleus	Eye Development Regulation Of Transcription By RNA Polymerase II Brain Development Animal Organ Morphogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Organ Development Neuron Development
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Attention deficit hyperactivity disorder symptom score ( 27663945) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Cholesterol, total ( 20686565) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) LDL cholesterol ( 18193044 19060906 20686565) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Obesity-related traits ( 23251661) Perceived unattractiveness to mosquitoes ( 28199695) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 25056061 29483656 23974872) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Total cholesterol levels ( 30275531) Triglyceride levels (parental genotype effect) ( 30255771) Triglyceride levels in response to fenofibrate treatment (parental genotype effect) ( 30255771) Triglycerides ( 18193044 19060906 20686565)
Interacting Genes		17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I	65 interacting genes: ARHGEF3 BCL6 BFSP2 C14orf119 C1orf109 CCM2L CDKN2C CHCHD2 CLCNKA CPNE7 EIF1AD EIF3B EIF3F EXOC8 GADD45GIP1 GEM GINS4 GPANK1 HOXB2 HOXB5 HOXC5 HOXC8 HOXD4 HSBP1L1 IFT20 IPO13 KDM1A KLHL38 LMO2 MAGOHB MAPK9 MBD3 MEIS2 MIPOL1 NCK2 NEK6 NUTF2 OSTF1 PACSIN2 PICK1 PIH1D2 PIK3R3 PKNOX1 PKNOX2 PPL RANBP3 RBX1 RIPPLY1 RIPPLY2 SCNM1 SERTAD1 SMARCD1 SPANXN2 SPANXN3 SPG21 TFIP11 TRIM41 TSEN15 TSSK3 TXNDC9 UBTFL1 USHBP1 USP20 WWOX ZNF330
Entrez ID		9670	80714
HPRD ID		13742	16287
Ensembl ID		ENSG00000117408	ENSG00000105717
Uniprot IDs		O94829	Q9BYU1
PDB IDs		2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?
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