ALX1 and IPO13

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ALX1	IPO13
Description		ALX homeobox 1	importin 13
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Golgi Apparatus Nuclear Body	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Protein Import Into Nucleus
Pathways
Drugs
Diseases		Frontonasal dysplasia
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300	17 interacting genes: ALX1 CRX EIF1AX GK HMBOX1 MAGOH NPSR1 NUP50 PAX3 PAX6 PBX4 PITX1 PSMA1 RAN RBM8A RPL5 UBE2I
Entrez ID		8092	9670
HPRD ID		03316	13742
Ensembl ID		ENSG00000180318	ENSG00000117408
Uniprot IDs		Q15699 V9HWA7	O94829
PDB IDs			2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?
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