FEZ2 and WWC1

Data Source:
BioGRID (two hybrid)

		FEZ2	WWC1
Description		fasciculation and elongation protein zeta 2	WW and C2 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Kinase Binding Molecular Adaptor Activity
	Biological Process	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Of Notch Receptor Target Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Negative Regulation Of Organ Growth
Pathways			Signaling by Hippo NOTCH3 Intracellular Domain Regulates Transcription
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758)	Adult body size ( 32376654) Cerebellum cortex volume ( 31530798) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Epithelial ovarian cancer ( 31469419) Mental health study participation (provided email address) ( 31263887) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Number of sexual partners ( 30643258) Periodontal microbiota ( 22699663) Regular attendance at a religious group ( 29970889) Type 2 diabetes nephropathy including microalbuminuria ( 30566433)
Interacting Genes		18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251	15 interacting genes: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 H3C1 KIAA0513 LRIF1 MAPK6 PRKCZ TNIK WWC2 WWC3
Entrez ID		9637	23286
HPRD ID		09213	10033
Ensembl ID		ENSG00000171055	ENSG00000113645
Uniprot IDs		Q9UHY8	Q8IX03
PDB IDs			2Z0U 6FB4 6FD0 6FJC 6FJD
Enriched GO Terms of Interacting Partners?
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