FEZ2 and NEK1

Data Source:
HPRD (two hybrid, in vitro)

		FEZ2	NEK1
Description		fasciculation and elongation protein zeta 2	NIMA related kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon	Pericentriolar Material Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Centriolar Satellite
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding 14-3-3 Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly	Protein Phosphorylation Cell Cycle Peptidyl-tyrosine Phosphorylation DNA Damage Response, Detection Of DNA Damage Cell Division Cilium Assembly
Pathways
Drugs			Fostamatinib
Diseases			Short rib-polydactyly syndrome
GWAS		Apolipoprotein A1 levels ( 32203549) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758)	Autism spectrum disorder or schizophrenia ( 28540026) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656) Supramarginal gyrus volume ( 31530798)
Interacting Genes		18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251	18 interacting genes: ATRX CSN2 CTNNAL1 EXOSC4 FEZ1 FEZ2 KIF3A LRRK1 LRRK2 MFHAS1 MRE11 PPP2R5A PTPRD SIRPA TP53BP1 TSC2 YWHAH ZNF350
Entrez ID		9637	4750
HPRD ID		09213	06847
Ensembl ID		ENSG00000171055	ENSG00000137601
Uniprot IDs		Q9UHY8	Q5JXL9 Q96PY6
PDB IDs			4APC 4B9D
Enriched GO Terms of Interacting Partners?
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