FEZ2 and CLASP2

Data Source:
BioGRID (two hybrid)

		FEZ2	CLASP2
Description		fasciculation and elongation protein zeta 2	cytoplasmic linker associated protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Spindle Microtubule Cytoplasmic Microtubule Plasma Membrane Focal Adhesion Cell Cortex Membrane Cell Leading Edge Ruffle Membrane Basal Cortex Mitotic Spindle
	Molecular Function	Protein Binding	Dystroglycan Binding Protein Binding Microtubule Binding Microtubule Plus-end Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly	Microtubule Cytoskeleton Organization Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Establishment Of Mitotic Spindle Localization Positive Regulation Of Exocytosis Cell Division Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Extracellular Matrix Disassembly Mitotic Spindle Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Role of ABL in ROBO-SLIT signaling RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758)	Metabolite levels ( 23823483)
Interacting Genes		18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251	15 interacting genes: ADRB2 AKT1 CCR4 CLIP1 CLIP2 CSNK2A1 ERBB2 FEZ1 FEZ2 MAPRE1 MAPRE2 MARK3 PYGM RBFOX2 SRPK2
Entrez ID		9637	23122
HPRD ID		09213	12054
Ensembl ID		ENSG00000171055	ENSG00000163539
Uniprot IDs		Q9UHY8	E3W994 E7ERI8 O75122
PDB IDs			3WOY 5NR4
Enriched GO Terms of Interacting Partners?
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