FEZ2 and TLK2

Data Source:
BioGRID (two hybrid)

		FEZ2	TLK2
Description		fasciculation and elongation protein zeta 2	tousled like kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon	Nucleus Intermediate Filament Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly	Regulation Of Chromatin Assembly Or Disassembly Chromatin Organization Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Cycle Chromosome Segregation Negative Regulation Of Autophagy Peptidyl-serine Phosphorylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Cellular Response To Gamma Radiation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758)	Heel bone mineral density ( 30598549) Lifespan ( 25918517)
Interacting Genes		18 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251	17 interacting genes: ASF1A ASF1B AURKA CEP70 DMAP1 FEZ1 FEZ2 FRMD6 GMCL1 IRF4 IRF7 MBP PAX5 PAX6 TLK1 UBE2I YWHAZ
Entrez ID		9637	11011
HPRD ID		09213	10527
Ensembl ID		ENSG00000171055	ENSG00000146872
Uniprot IDs		Q9UHY8	B4DUC2 J3QLK5 Q86UE8
PDB IDs			5O0Y
Enriched GO Terms of Interacting Partners?
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