TP53I3 and UBR1

		TP53I3	UBR1
Description		tumor protein p53 inducible protein 3	ubiquitin protein ligase E3 component n-recognin 1
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GO Annotations	Cellular Component	Cytosol	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol
	Molecular Function	NADPH:quinone Reductase Activity Protein Homodimerization Activity Quinone Binding NADPH Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding
	Biological Process	NADP Metabolic Process Regulation Of Apoptotic Process	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Johanson-Blizzard syndrome
GWAS			MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)
Interacting Genes		6 interacting genes: EEF1G FUNDC2 GPX3 MDM2 UBR1 UNC119	28 interacting genes: ANXA3 ARL15 ARL3 ARL4D BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NTAN1 NTAQ1 NUDT3 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2
Entrez ID		9540	197131
HPRD ID		05527	09342
Ensembl ID		ENSG00000115129	ENSG00000159459
Uniprot IDs		B4DMQ7 Q53FA7	Q8IWV7
PDB IDs		2J8Z 2OBY	3NY1 5TDC
Enriched GO Terms of Interacting Partners?
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