UBR1 and ARL4D

		UBR1	ARL4D
Description		ubiquitin protein ligase E3 component n-recognin 1	ADP ribosylation factor like GTPase 4D
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol	Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Johanson-Blizzard syndrome
GWAS		MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)
Interacting Genes		28 interacting genes: ANXA3 ARL15 ARL3 ARL4D BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NTAN1 NTAQ1 NUDT3 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2	22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119
Entrez ID		197131	379
HPRD ID		09342	02842
Ensembl ID		ENSG00000159459	ENSG00000175906
Uniprot IDs		Q8IWV7	P49703
PDB IDs		3NY1 5TDC
Enriched GO Terms of Interacting Partners?
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