GRHPR and LSM1

Data Source:
HPRD (two hybrid)

		GRHPR	LSM1
Description		glyoxylate and hydroxypyruvate reductase	LSM1 homolog, mRNA degradation associated
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Exosome Catalytic Complex	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Glycerate Dehydrogenase Activity Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP+) Activity Protein Homodimerization Activity NAD Binding NADPH Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Excretion Cellular Nitrogen Compound Metabolic Process Glyoxylate Metabolic Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways		Glyoxylate metabolism and glycine degradation	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases		Primary hyperoxaluria (HP)
GWAS		Bipolar disorder ( 31043756) Chronotype ( 30696823) Morning person ( 30696823) Severe bacterial meningitis ( 31092817)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		6 interacting genes: CDC7 FOS GLS2 LIG4 LSM1 PTH2R	32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		9380	27257
HPRD ID		05052	06281
Ensembl ID		ENSG00000137106	ENSG00000175324
Uniprot IDs		A0A384N605 Q9UBQ7	A0A0S2Z590 O15116
PDB IDs		2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?
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