LSM1 and GSTA4

Data Source:
BioGRID (two hybrid)

		LSM1	GSTA4
Description		LSM1 homolog, mRNA degradation associated	glutathione S-transferase alpha 4
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Cytosol
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Glutathione Transferase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	Glutathione conjugation
Drugs			Glutathione
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Arterial stiffness index ( 31235810) Epilepsy (remission after treatment) ( 23962720) Nose size ( 27182965) Staphylococcus aureus nasal carriage (intermittent) ( 26569114)
Interacting Genes		32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	5 interacting genes: C2orf50 GAS8 GSTA2 LSM1 NTAQ1
Entrez ID		27257	2941
HPRD ID		06281	06899
Ensembl ID		ENSG00000175324	ENSG00000170899
Uniprot IDs		A0A0S2Z590 O15116	A0A024RD58 O15217
PDB IDs			1GUL 1GUM 3IK7
Enriched GO Terms of Interacting Partners?
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