LSM1 and RRP1B

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LSM1	RRP1B
Description		LSM1 homolog, mRNA degradation associated	ribosomal RNA processing 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Preribosome, Large Subunit Precursor Preribosome, Small Subunit Precursor
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Transcription Coactivator Activity RNA Binding Protein Binding
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	RRNA Processing MRNA Processing Apoptotic Process RNA Splicing Negative Regulation Of Phosphatase Activity Viral Process Negative Regulation Of GTPase Activity Positive Regulation Of Apoptotic Process Regulation Of RNA Splicing Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Virus
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Diastolic blood pressure ( 28135244 27618447) Mean corpuscular hemoglobin ( 27863252) Refractive error ( 32231278) Systolic blood pressure ( 27618447)
Interacting Genes		32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	4 interacting genes: CSNK2A1 LSM1 PPP1CC SRPK2
Entrez ID		27257	23076
HPRD ID		06281	10009
Ensembl ID		ENSG00000175324	ENSG00000160208
Uniprot IDs		A0A0S2Z590 O15116	Q14684
PDB IDs
Enriched GO Terms of Interacting Partners?
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